Summary: For patients receiving operative treatment for a single extremity fracture, using acetaminophen alone for post-discharge analgesia may not be inferior for providing satisfaction with treatment compared to post-discharge analgesia with acetaminophen plus tramadol; while treatment with acetaminophen alone might be associated with a lower risk for side effects and for medication habit-forming.

https://www.ncbi.nlm.nih.gov/m/pubmed/29135664/

Strength of Recommendation = B

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