Summary: For children (between ages 2 and 18 years old) with a heart murmur detected on seated physical exam, complete disappearance of the murmur on standing may be more highly predictive that the murmur is benign and that additional testing is not needed than other traditionally-taught clinical features used to distinguish physiologic from pathologic murmurs.

https://www.ncbi.nlm.nih.gov/m/pubmed/29133490/

Strength of Recommendation = C

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