Summary: For children with seeking emergency care for an acute exacerbation of asthma, treatment with a single dose of oral dexamethasone (0.3 mg/kg) may be associated with the no differences on the Pediatric Respiratory Assessment Measure (PRAM) score at 4 days compared to treatment with oral prednisolone (1 mg/kg per day for 3 days), but treatment with dexamethasone can be accomplished with fewer doses of medication (once vs daily for 3 days); with dexamethasone associated with lower likelihood of vomiting but a higher likelihood of needing further systemic steroids within 14 days.

https://www.ncbi.nlm.nih.gov/m/pubmed/26460983/

Strength of Recommendation = B

Advertisements