Summary: For women between 22 to 27 years of age who have a pap test showing atypical squamous cells of undetermined significance (ASCUS) or low-grade squamous intraepithelial lesion (LSIL), following up with repeat cervical cytology at 6 months may be associated with the same rates of invasive cervical cancer at 6.5 years as following up with colposcopy and biopsy at 6 months, at potentially lower cost.

Strength of Recommendation = C