Summary: For patients with chronic obstructive pulmonary disease (COPD) and moderate resting or exertional oxygen desaturation, an approach of not using supplemental oxygen may be associated with the same life expectancy and the same likelihood of hospitalization or COPD exacerbation as an approach of using supplemental oxygen, without the risks associated with supplemental oxygen use (such as tripping over equipment, fires or burns).

Strength of Recommendation = B