Summary: For patients with moderate to severe acute renal colic, intramuscular diclofenac (75 mg) or intravenous paracetamol (1g) may be more likely to provide a 50% reduction in pain at 30 minutes than low-dose intravenous morphine (0.1 mg/kg), and both diclofenac and paracetamol may be associated with a lower likelihood of adverse events compared to morphine.

Strength of Recommendation = B