Summary: For critically ill children, waiting at least one week before starting parenteral nutrition appears to be associated with a lower rate of new infections, a shorter ICU stay, a shorter duration of mechanical ventilation, a smaller risk of needing renal replacement therapy, and a shorter overall hospital stay compared to early initiation of parenteral nutrition (ie, starting parenteral nutrition within 24 hours of ICU admission).

http://www.ncbi.nlm.nih.gov/m/pubmed/26975590/

Strength of Recommendation = B

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