Summary: Older data suggests that for men with a recent coronary event, avoiding replacement of saturated fats with omega 6 linoleic acid might actually be associated with lower rates of death, cardiovascular disease, and coronary heart disease. (In other words, for men with a recent coronary event, a diet replacing saturated fats with omega 6 linoleic acid from safflower oil and safflower oil polyunsaturated margarine may be associated with HIGHER rates of death, cardiovascular disease, and coronary heart disease).

http://www.ncbi.nlm.nih.gov/m/pubmed/23386268/

Strength of Recommendation = C

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