Summary: For adults with unwitnessed out-of-hospital cardiac arrest due to shock-refractory ventricular fibrillation or pulseless ventricular tachycardia, there appears to be no difference in rates of survival to hospital discharge between patients treated with placebo, and patients treated with amiodarone or lidocaine; however patients treated with amiodarone may be more likely to require temporary cardiac pacing.

Strength of Recommendation = B