Summary: For patients on anticoagulation with warfarin who have an elevated international normalized ratio (INR) between 4.5 and 10, withholding warfarin and giving 1 mg oral vitamin K is more likely to result in a therapeutic INR at 24 hours than withholding warfarin and giving 1 mg subcutaneous vitamin K.

www.ncbi.nlm.nih.gov/m/pubmed/12186515/

Strength of Recommendation = B

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