Summary: For adults with acute uncomplicated respiratory infections, a delayed-prescription strategy (ie, prescribing an antibiotic with instructions to start the medication only if symptoms get worse) may lead to significantly decreased use of antibiotics, without any clinically significant increase in the duration of severe symptoms compared to patients given immediate antibiotic treatment.

http://www.ncbi.nlm.nih.gov/m/pubmed/26719947/

Strength of Recommendation = B

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