Summary: For patients with acute COPD, and treated at presentation with IV methylprednisolone + a broad-spectrum antibiotic, treatment with a subsequent 5-day course of oral prednisone 40 mg daily works just as well for preventing subsequent COPD exacerbations as a 14 day course of prednisone 40 mg daily, but with a significantly lower overall glucocorticoid exposure.

http://www.ncbi.nlm.nih.gov/m/pubmed/23695200/

Strength of Recommendation = B

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