Summary: For adult women with typical symptoms of a urinary tract infection (eg, dysuria, frequency, or urgency) and without any risk factors for complication (eg, fever, loin tenderness, pregnancy, kidney disease, or recent urinary infection or catheterization), treatment with ibuprofen 300 mg 3x daily for 3 days may provide the same likelihood of recovery as treatment with a single dose of fosfomycin, thus allowing treatment without the need for an antibiotic prescription (although women treated with ibuprofen may take about 1 day longer to achieve full remission of symptoms).

Strength of Recommendation = B