Summary: A more restrictive use of red blood cell (RBC) transfusions (eg, using a hemoglobin threshold of <7.0 g/dL) may be associated with a lower risk of serious infections than a more liberal approach to transfusions, especially for orthopedic patients and for patients presenting with sepsis.

http://www.ncbi.nlm.nih.gov/m/pubmed/24691607/

Strength of Recommendation = A

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