Summary: For patient with atrial fibrillation on oral anticoagulation (OAC), avoiding the use of aspirin (ASA) may be associated with a lower risk of bleeding (compared to treatment with OAC + ASA), without any increased risk of death (however, the statistical power of this observational study was too low to clearly address whether this is also true for patients with previous atherosclerotic disease).

Strength of Recommendation = B