Summary: For patients with intra-abdominal infections who have had an appropriate source-control surgical procedure, fixed-duration antibiotic therapy (approximately 4 days) may lead to similar outcomes (including rates of surgical-site infection, recurrent intra-abdominal infection, or death) compared to treating with antibiotics until 2 days after the resolution of fever, leukocytosis, and ileus, with a maximum of 10 days of therapy, while allowing for decreased overall antibiotic exposure.

Strength of Recommendation = B